A comprehensive review of your aging and evolving gut microbiome

A study recently published in the journal Cell is teeming with incredible insights in to how/why our microbiome evolves with us as we age.  There are quite a few key takeaways from this study, which is open access and free to read here. While focus has been on the gut microbiome, other microbial communities throughout … Continue reading A comprehensive review of your aging and evolving gut microbiome

Could sealing the blood brain barrier and gut really be this easy?

A study I posted recently on the Facebook page generated a decent discussion on how traumatic brain injury promotes a leaky gut.  The interesting take-home message from the study is that one long term symptom of traumatic brain injury(TBI) is "leaky gut". The theoretical trek from there is that endotoxin can then cross the gut … Continue reading Could sealing the blood brain barrier and gut really be this easy?

New study sheds light on circadian rhythms and autoimmunity

A new study showing the relationship between the circadian clocks and autoimmunity hints at a potential lifestyle fix to help quell the fires of autoimmunity.  The study, published in Nature Communications, found that disruption of the circadian clock in myeloid cells by removal of the gene BMAL1,  which teams up with CLOCK to function as … Continue reading New study sheds light on circadian rhythms and autoimmunity

The shocking reasons why calorie restriction may not prolong your life

It's almost dogma in longevity research that caloric restriction will extend your lifespan.  Granted, I think everyone agrees that humans won't see the same level of life extension under caloric restriction as mice, primarily because we experience a slower rate of epigenetic drift. It's also unlikely, although still plausible, that humans will spend a large … Continue reading The shocking reasons why calorie restriction may not prolong your life

This process is key to regulating gut inflammation

For those people dealing with gut problems, every day is an adventure.  Fortunately, there are a number of dietary approaches that can help a great deal with symptom management. Whether you're talking about the Specific Carbohydrate diet(SCD Diet), low FODMAP diet, or the GAPS diet, many people can do things they weren't previously able to … Continue reading This process is key to regulating gut inflammation