A number of studies have linked Parkinson's disease with issues arising in the gut. While we don't know the direction of causality, if the gut changes the brain or vice versa, a small amount of evidence indicates that the changes may be initiated in the gut. A study published yesterday indicates that one of the … Continue reading Further evidence the gut may be involved in Parkinson’s disease
While I've never personally watched a loved one develop and succumb to Alzheimer's disease, the devastation it leaves on individuals and families is obvious. I can't imagine not being able to remember recent events, forgetting who my child is, and losing executive functions to the point of death. Even worse is the fact that it's … Continue reading Knowing this may help prevent Alzheimer’s…and potentially reverse it
Some of you may recall the recent blog I did going over my aging biomarkers. If you didn't read it, you can catch it right here. Towards the end of the blog, I discussed that one of the reasons my telomere test showed much better results than my DNA methylation test is that I fasted … Continue reading Fasting, longevity, and telomeres: The regenerating effects of prolonged fasting
Who doesn't want healthy digestion? Of course most people would answer that they do, but most people take healthy digestion for granted. Who could really blame them, who ever thinks about their digestion until something goes wrong with it? For the most part, digestion is just one of those automatic processes we never give a … Continue reading How circadian rhythms promote healthy digestion
Over the last decade or 2 there's been a bit of a renaissance on the hunt for the fountain of youth. A large part of this drive can be laid at the feet of a new paradigm on aging. We no longer look at aging as a strictly time-dependent process. As the science in to … Continue reading Biological age from a picture? Pros, cons, and future directions for Young.AI
A recent study published in The Journals of Gernontology Series A found an association between poor oral health and frailty in the elderly. T he study found that elderly people who had poor status in 3 or more measures of oral frailty(# of natural teeth, chewing ability, tongue pressure, difficulties in eating or swallowing, and … Continue reading Oral health, chronic disease, and longevity
As research in to human aging and the mechanisms behind it grow, there's a need to address the big fat albatross around the neck of gerontology. The albatross is that until we identify some valid biomarkers of human aging, we must rely on the data in animal models and epidemiological research in humans. Currently, there … Continue reading Aging Biomarkers: Am I 7 years older or 10 years younger?
A study recently published in the journal Cell is teeming with incredible insights in to how/why our microbiome evolves with us as we age. There are quite a few key takeaways from this study, which is open access and free to read here. While focus has been on the gut microbiome, other microbial communities throughout … Continue reading A comprehensive review of your aging and evolving gut microbiome
A study I posted recently on the Facebook page generated a decent discussion on how traumatic brain injury promotes a leaky gut. The interesting take-home message from the study is that one long term symptom of traumatic brain injury(TBI) is "leaky gut". The theoretical trek from there is that endotoxin can then cross the gut … Continue reading Could sealing the blood brain barrier and gut really be this easy?
A new study showing the relationship between the circadian clocks and autoimmunity hints at a potential lifestyle fix to help quell the fires of autoimmunity. The study, published in Nature Communications, found that disruption of the circadian clock in myeloid cells by removal of the gene BMAL1, which teams up with CLOCK to function as … Continue reading New study sheds light on circadian rhythms and autoimmunity