Circadian rhythms and aging

https://www.nature.com/articles/s41467-021-22922-6#citeas Discuss how the nutrient sensing pathways are the hot mechanisms to delay age-related decline(SIRT1(NAD+), AMPK, mTOR, IIS) Mention how this is tissue specific and more complex than taking a supplement(mTOR inhibition in adipose tissue vs muscle) Discuss how nutrient sensing pathways play a role in circadian rhythms Clock/Bmal1-->NAMPT-->NAD+-->SIRT1-->Binds Clock/Bmal1 & degrades Per2 AMPK-->inhibits Cry1 … Continue reading Circadian rhythms and aging

The secret to eliminating small intestinal bacterial overgrowth

Small intestinal bacterial overgrowth (SIBO) is a condition where excess bacteria grow in the small intestine. While there are normally trillions of bacteria in the gut, their numbers are low in the small intestine of healthy people. Different areas of the gut contain varying amounts of microbes, expressed as log colony-forming units per gram(CFU/g). In … Continue reading The secret to eliminating small intestinal bacterial overgrowth