Mitochondria are known as the powerhouses of our cells due to their high energy generating capacity in the form of adenine triphosphate(ATP). In fact, 90% of the ATP generated in our body is made in the mitochondria via the Krebs cycle and electron transport chain. Cell types vary in their number of mitochondria, typically based … Continue reading Amazing mitochondria: More than just cellular powerhouses
Truth be told, I've mostly owned Fitbit products as wearable activity trackers. I've owned a Fitbit Ultra and a Fitbit One that lasted me a combined 4+ years and a Basis Peak that lasted about 8 months before I got tired of it. I wanted to upgrade to something that had heart rate as a … Continue reading Fitbit Charge 2 HR: An indispensable tool for lifestyle optimization
Image source The great thing about science is that it causes us to evolve our thinking on topics over time. When we look back at the days of bloodletting as a serious form of medicine, it's easy to laugh at the simplistic approach to a very complex topic. It probably wasn't easy to laugh for … Continue reading Why We Sleep: A book everyone should read
Some of you may recall the recent blog I did going over my aging biomarkers. If you didn't read it, you can catch it right here. Towards the end of the blog, I discussed that one of the reasons my telomere test showed much better results than my DNA methylation test is that I fasted … Continue reading Fasting, longevity, and telomeres: The regenerating effects of prolonged fasting
Over the last decade or 2 there's been a bit of a renaissance on the hunt for the fountain of youth. A large part of this drive can be laid at the feet of a new paradigm on aging. We no longer look at aging as a strictly time-dependent process. As the science in to … Continue reading Biological age from a picture? Pros, cons, and future directions for Young.AI
A recent study published in The Journals of Gernontology Series A found an association between poor oral health and frailty in the elderly. T he study found that elderly people who had poor status in 3 or more measures of oral frailty(# of natural teeth, chewing ability, tongue pressure, difficulties in eating or swallowing, and … Continue reading Oral health, chronic disease, and longevity
As research in to human aging and the mechanisms behind it grow, there's a need to address the big fat albatross around the neck of gerontology. The albatross is that until we identify some valid biomarkers of human aging, we must rely on the data in animal models and epidemiological research in humans. Currently, there … Continue reading Aging Biomarkers: Am I 7 years older or 10 years younger?
A study recently published in the journal Cell is teeming with incredible insights in to how/why our microbiome evolves with us as we age. There are quite a few key takeaways from this study, which is open access and free to read here. While focus has been on the gut microbiome, other microbial communities throughout … Continue reading A comprehensive review of your aging and evolving gut microbiome
A study I posted recently on the Facebook page generated a decent discussion on how traumatic brain injury promotes a leaky gut. The interesting take-home message from the study is that one long term symptom of traumatic brain injury(TBI) is "leaky gut". The theoretical trek from there is that endotoxin can then cross the gut … Continue reading Could sealing the blood brain barrier and gut really be this easy?
If it seems as though research in to aging is exploding right now, that's because it is. Over the last few decades, our paradigm on aging has experienced a pretty substantial shift. What was once believed to be an inevitable process dictated solely on the passage of time and the genetic hand you've been dealt … Continue reading Healthy aging requires proper circadian rhythms