Fasting, longevity, and telomeres: The regenerating effects of prolonged fasting

Some of you may recall the recent blog I did going over my aging biomarkers.  If you didn't read it, you can catch it right here.  Towards the end of the blog, I discussed that one of the reasons my telomere test showed much better results than my DNA methylation test is that I fasted … Continue reading Fasting, longevity, and telomeres: The regenerating effects of prolonged fasting

Aging Biomarkers: Am I 7 years older or 10 years younger?

As research in to human aging and the mechanisms behind it grow, there's a need to address the big fat albatross around the neck of gerontology.  The albatross is that until we identify some valid biomarkers of human aging, we must rely on the data in animal models and epidemiological research in humans. Currently, there … Continue reading Aging Biomarkers: Am I 7 years older or 10 years younger?

A comprehensive review of your aging and evolving gut microbiome

A study recently published in the journal Cell is teeming with incredible insights in to how/why our microbiome evolves with us as we age.  There are quite a few key takeaways from this study, which is open access and free to read here. While focus has been on the gut microbiome, other microbial communities throughout … Continue reading A comprehensive review of your aging and evolving gut microbiome

Could sealing the blood brain barrier and gut really be this easy?

A study I posted recently on the Facebook page generated a decent discussion on how traumatic brain injury promotes a leaky gut.  The interesting take-home message from the study is that one long term symptom of traumatic brain injury(TBI) is "leaky gut". The theoretical trek from there is that endotoxin can then cross the gut … Continue reading Could sealing the blood brain barrier and gut really be this easy?

The shocking reasons why calorie restriction may not prolong your life

It's almost dogma in longevity research that caloric restriction will extend your lifespan.  Granted, I think everyone agrees that humans won't see the same level of life extension under caloric restriction as mice, primarily because we experience a slower rate of epigenetic drift. It's also unlikely, although still plausible, that humans will spend a large … Continue reading The shocking reasons why calorie restriction may not prolong your life

Is there a simpler alternative to calorie restriction for longevity?

Calorie restriction and fasting are 2 of the hottest areas of research in longevity and age rejuvenation.  In fact, you probably know someone who has dabbled in, or who is currently dabbling in, one or the other.  These techniques, whether you're talking about calorie restriction, fasting, or protein restriction, fall under the general umbrella of … Continue reading Is there a simpler alternative to calorie restriction for longevity?